Homeopathy, or Systems Modulation Medicine, is a therapeutic method based on the analogical principle of similarity and the law of hormesis.
Hormesis can be considered an adaptive function characterized by a dose-dependent biphasic response (Calabrese and Baldwin, 2002).
Very synthetically, the hormetic law defines that low doses of a substance stimulate, high doses of the same substance inhibit (by low and high doses we mean low dynamic induction and high dynamic induction) (1)dynamic induction: process by which at each dilution step kinetic force is imparted to the solution through devices called dynamizers. Since the kinetic energy supplied is proportional to the number of dilutions, to prepare a 30 CH a greater kinetic energy will be required than for a 4 CH..
In recent times, the most accredited researcher with the most publications on the subject is Dr. Edward J. Calabrese, professor of toxicology at the University of Massachusetts, who has been studying the phenomenon for almost twenty years, and has demonstrated its validity for about 5.000 substances, which precisely possess this ambivalent behavior. In Homeopathy, numerous substances of mineral, vegetal and animal origin have been studied, which possess such biphasic characteristics, substances that have been codified in the materia medica and applied in clinical protocols.
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Furthermore, the homeopathic method also includes the process of dynamization or dynamic activation which consists in subjecting the substance to a precise and sequential series of succussions, agitations or jolts, pharmacologically standardized. This procedure is essential to obtain an effective and complete drug. This has been seen in the case of interleukins: recent studies have observed that the dilution of interleukin alone was not sufficient to activate its specific therapeutic role which became effective only after the dynamization process.
The fundamental principle on which Homeopathy is based is based on the law of similarity: like cures like, that is to say that a substance that during experimentation on healthy people causes a series of symptoms, will be able to remove them when they appear in a sick person, provided that the substance is evaluated according to the hormetic law and processed according to dynamic induction. Experimentation carried out over decades has codified the pathogenesis of numerous substances that have then been catalogued in the homeopathic materia medica. Homeopathy, therefore, uses drugs regularly registered with the AIFA, (Italian Medicines Agency) as required by Legislative Decree 219 which implements European Directive 2001/83/CE, drugs that are prescribed on the basis of the hormetic law and the pharmaceutical technique of dilution associated with the dynamic activation process. The therapeutic protocols are set on the basis of the above conditions and in the light of 200 years of experience that has gradually changed and adapted to the most recent discoveries in the medical, chemical and physical fields.
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These protocols are constantly evolving due to scientific upgrades. It can also be added that homeopathic drugs, due to their intrinsic structure, have the ability to down-regulate or up-regulate numerous biological elements of the body, with particular focus on the elements that make up the PNEI (PsychoNeuroEndocrineImmunological) axis, recently also using substances of biological and immunological origin (elements of the Krebs cycle, Cytokines, growth factors, neurotransmitters, etc.) with surprising results considering the dose-dependency mechanism. Homeopathy is a highly current therapeutic method and consistent with an evolutionary and green vision of Medicine, because it uses mainly active ingredients of vegetal and mineral origin at low doses and because it is located within the increasingly widespread concept of Slow Medicine: "less is better than more", a concept that is present in all environmental projects aimed at the survival of the planet and the human system.
Of more recent codification, homotoxicology has taken from homeopathy the pharmacological method based on hormesis and dynamic activation, but it has differentiated itself in its diagnostic methodological approach.
Homotoxicology considers the presence of homotoxins as the basis of pathology, against which the organism carries out defensive phases which are divided into:
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1. Excretory phase: characterized by physiological excretions through the tissues of the three embryonic layers and the emunctories.
2. Reaction phase: This phase is characterized by pathologically intensified reactions: fever, pain, inflammation.
3. Deposition phase: in this phase there are non-malignant deposits, which can give rise to even chronic disorders
4. Impregnation phase: this is a silent phase, during which homotoxins penetrate the cells; cellular structures and enzymes are destroyed, the functions of the cell membrane can be altered. This phase can remain latent for a long time, but it produces a “locus minoris resistenteae”.
5. Degeneration Phase: In this phase homotoxins destroy intracellular structures. Degeneration products begin to accumulate. In this phase the disorder changes from functional to organic.
6. Neoplasm phase: neoplasms are produced. For Reckeweg, the neoplasm phase represents the organism's attempt to stay alive as long as possible, despite repeated lesional events of all kinds. The toxins that invade the organism are condensed in the carcinoma.
Homotoxicological treatment therefore aims to remove toxins as much as possible and to reverse the phases described above, a process which is defined as regressive vicariation.
Therefore, in the homotoxicological concept, disease must be understood as the biological defensive expression that the organism puts in place to eliminate the various toxins.
Endogenous homotoxins are the toxic wastes of intermediary metabolism while exogenous homotoxins are the toxic wastes of bacteria, viruses, pesticides, some food additives, some preservatives.
Homotoxicology uses pharmaceutical products, mainly compound homotoxicological drugs, which can be in the form of drops, vials, capsules and ointments for topical use.
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